SCHEMBL11259159

SCHEMBL11259159

COc1cc(C(C)(C)C(C)C)c(S)cc1C(C)(C)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
HTR2A P28223 2/20 0.34
HTR2C P28335 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8749337 0.78 ALOX15 (0.61) LMNATP53CYP3A4HPGDALOX15
SCHEMBL11259141 0.68 LMNA (0.37) LMNATP53CYP3A4HPGDALOX15
SCHEMBL22431504 0.67 CA1 (0.48) TP53HPGD
SCHEMBL398164 0.65 CYP3A4 (0.74) LMNATP53CYP3A4HPGDALOX15
SCHEMBL20756625 0.64 HTR2A (0.62) LMNATP53CYP3A4HPGDALOX15
SCHEMBL12781654 0.62 CYP3A4 (0.68) LMNATP53CYP3A4HPGDALOX15
SCHEMBL13939800 0.62 ALOX15 (0.68) LMNATP53CYP3A4HPGDALOX15
SCHEMBL9918371 0.62 L3MBTL1 (0.47) LMNACYP3A4HTR2AHTR2C
SCHEMBL10907576 0.61 MAPT (0.37) LMNATP53CYP3A4HPGDALOX15
SCHEMBL2946854 0.61 CYP3A4 (0.60) LMNATP53CYP3A4HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4351897-A Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1982-09-28 US disclosed