Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271891 | 0.99 | HTT (0.36) | HTTMEN1KMT2AABL1POLB | |
| SCHEMBL11259600 | 0.87 | NPSR1 (0.34) | MEN1KMT2ACYP1A2CYP2D6KDM4E | |
| SCHEMBL11264866 | 0.87 | ABCB11 (0.41) | HTTMEN1KMT2APOLBLMNA | |
| SCHEMBL11265822 | 0.86 | NPSR1 (0.34) | MEN1KMT2ACYP1A2CYP2D6KDM4E | |
| SCHEMBL11270376 | 0.86 | ABCB11 (0.42) | HTTMEN1KMT2APOLBLMNA | |
| SCHEMBL11264418 | 0.85 | TP53 (0.32) | HTTMEN1KMT2ALMNACYP2D6 | |
| SCHEMBL11257358 | 0.85 | TP53 (0.32) | HTTMEN1KMT2ALMNACYP2D6 | |
| SCHEMBL11267380 | 0.85 | TP53 (0.32) | HTTMEN1KMT2ALMNACYP2D6 | |
| SCHEMBL11273749 | 0.85 | TP53 (0.32) | HTTMEN1KMT2ALMNACYP2D6 | |
| SCHEMBL11263429 | 0.85 | TP53 (0.32) | HTTMEN1KMT2ALMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |