Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.55 |
| ▸ | EGFR | P00533 | 5/20 | 0.51 |
| ▸ | FADS1 | O60427 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254363 | 0.87 | EGFR (0.52) | MAP4K4EGFRSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL11245980 | 0.87 | EGFR (0.57) | MAP4K4EGFRPIK3CDPIK3R1SMN1; SMN2 | |
| SCHEMBL11249827 | 0.87 | GBA1 (0.57) | MAP4K4EGFRSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL11258725 | 0.81 | RAB9A (0.54) | EGFRSMN1; SMN2MAPK1RAB9ANPC1 | |
| SCHEMBL11240408 | 0.80 | LDHA (0.49) | MAP4K4EGFRSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL11248987 | 0.80 | SMN1; SMN2 (0.53) | EGFRSMN1; SMN2MAPK1RAB9ANPC1 | |
| SCHEMBL11260225 | 0.80 | GBA1 (0.55) | MAP4K4EGFRSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL11257318 | 0.79 | PIK3CD (0.72) | MAP4K4EGFRFADS1LCKPIK3CD | |
| SCHEMBL11261278 | 0.78 | EGFR (0.52) | MAP4K4EGFRFADS1LCKPIK3CD | |
| SCHEMBL11252948 | 0.78 | PIK3CD (0.67) | MAP4K4EGFRFADS1LCKPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |