Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | STK10 | O94804 | 4/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 4/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.40 |
| ▸ | WEE1 | P30291 | 3/20 | 0.40 |
| ▸ | TGM2 | P21980 | 3/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260054 | 0.85 | CES1 (0.47) | CES1NSD2BCHEDAOGSK3B | |
| SCHEMBL261439 | 0.82 | GSK3B (0.52) | CES1NSD2BCHEDAOGSK3B | |
| SCHEMBL7828007 | 0.82 | CES1 (0.38) | CES1NSD2BCHEDAOGSK3B | |
| Phthalimide SCHEMBL1501259 | 0.78 | GSK3B (0.60) | CES1NSD2BCHEDAOGSK3B | |
| SCHEMBL3988383 | 0.77 | ADORA2A (0.46) | GSK3BCHEK1WEE1 | |
| SCHEMBL11222151 | 0.75 | CES1 (0.47) | CES1NSD2BCHEDAORET | |
| Biphenyl SCHEMBL20954045 | 0.73 | GSK3B (0.52) | CES1NSD2BCHEDAOGSK3B | |
| SCHEMBL11669701 | 0.72 | S100A4 (0.56) | GSK3BCHEK1WEE1 | |
| SCHEMBL30823795 | 0.71 | DAO (0.39) | CES1NSD2BCHEDAOGSK3B | |
| SCHEMBL29497778 | 0.70 | GSK3B (0.67) | CES1BCHEGSK3BDYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317929-A | Tetraphenylketazines and isoindolinone pigments obtained therefrom | CIBA-GEIGY CORPORATION (US) | 1982-03-02 | — | — | US | disclosed |
| US-4231931-A | YELLOW TO RED HUES | CIBA-GEIGY CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4065462-A | ORGANIC PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4016157-A | COLORING PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |