SCHEMBL7828007

SCHEMBL7828007

N=C1NC(=N)c2c(Cl)cccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.38
NSD2 O96028 2/20 0.38
BCHE P06276 1/20 0.38
DAO P14920 1/20 0.38
PDK2 Q15119 2/20 0.37
CYP2A6 P11509 2/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
RET P07949 1/20 0.32
GRK5 P34947 1/20 0.32
TYRO3 Q06418 1/20 0.32
DYRK1B Q9Y463 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
STK10 O94804 2/20 0.32
GSK3B P49841 2/20 0.32
SLK Q9H2G2 2/20 0.32
IDO1 P14902 3/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11260054 0.82 CES1 (0.47) CES1NSD2BCHEDAORET
SCHEMBL11259415 0.82 CES1 (0.47) CES1NSD2BCHEDAORET
SCHEMBL7816411 0.79 CYP1A2 (0.46) CES1NSD2BCHEDAOCYP2A6
SCHEMBL11856814 0.76 PTGS2 (0.36) CYP1A2KMT2AWEE1
SCHEMBL13297043 0.76 CES1 (0.39) CES1CYP2A6CYP1A2
SCHEMBL9148787 0.74 CES1 (0.38) CES1
SCHEMBL7816308 0.74 ADORA2A (0.41) PDK2CYP1A2POLBKMT2ATSHR
SCHEMBL18663478 0.74 CA1 (0.41) PDK2DYRK1BCHEK1WEE1
SCHEMBL18663481 0.74 TDP2 (0.35)
SCHEMBL7815737 0.74 CA1 (0.41) DAOPDK2CYP2A6CYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9908992-B2 Curing agents for fluoroelastomers E I DU PONT DE NEMOURS AND COMPANY (US) 2018-03-06 US disclosed
EP-3205690-A1 CURING AGENTS FOR FLUOROELASTOMERS E. I. du Pont de Nemours and Company (US) 2017-08-16 EP disclosed
US-20170088693-A1 Curing Agents For Fluoroelastomers DUPONT SPECIALTY PRODUCTS USA, LLC 2017-03-30 US disclosed
EP-0679640-B1 Carboxylate and heat-sensitive recording material using same MITSUI CHEMICALS INC (JP) 2001-08-08 EP disclosed
US-5756247-A PHOTOCONDUCTOR OBTAINED BY HYDROXYLATION WITH ACID PASTING GALLIUM PHTHALOCYANINE; CHARGEABILITY, IMAGE; SEMICONDUCTOR LASER PRINTER FUJI XEROX CO., LTD. (JP) 1998-05-26 US disclosed
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5663327-A Hydroxygallium phthalocyanine crystal, process for producing the same, and electrophotographic photoreceptor containing the same FUJI XEROX CO., LTD. (JP) 1997-09-02 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed
US-5280183-A Microelectronic device employing multiring phthalocyanine compound EDISON POLYMER INNOVATION CORPORATION (US) 1994-01-18 US disclosed
US-4414395-A REACTING AN IMINOISOINDOLE WITH HYDRAZINE CIBA-GEIGY CORPORATION (US) 1983-11-08 US disclosed
EP-0036387-A2 Process for the preparation of hydrazono-isoindolines CIBA-GEIGY AG (CH) 1981-09-23 EP disclosed
EP-0025908-A1 1:1-Nickel complexes and their use BASF Aktiengesellschaft (DE) 1981-04-01 EP disclosed
EP-0000373-A1 Imidazole carboxylic acids and derivatives thereof, process for their preparation and their use as plant growth regulants or plant protection agents HOECHST AKTIENGESELLSCHAFT (DE) 1979-01-24 EP disclosed
US-4122261-A Polycyclic iminoisoindoline chelates STERLING DRUG INC. (US) 1978-10-24 US disclosed
US-4116959-A ISOINDOLINE PIGMENTS CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-4066653-A 1-IMINO-3-(4-IMINO-5-THIAZOLIDINYLIDENE)ISOINDOLINES STERLING DRUG INC. (US) 1978-01-03 US disclosed
US-4051099-A ISOINDOLES CIBA-GEIGY CORPORATION (US) 1977-09-27 US disclosed
US-3993658-A Thiazolidinylidene-isoindolines STERLING DRUG INC. (US) 1976-11-23 US disclosed
US-3966753-A Thiazolidinylidene isoindoline pigments STERLING DRUG INC. (US) 1976-06-29 US disclosed