Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252689 | 0.86 | TDP1 (0.41) | PTGDR2MAPTTDP1POLBSMN1; SMN2 | |
| SCHEMBL11259706 | 0.80 | L3MBTL1 (0.46) | PTGDR2TDP1POLBSMN1; SMN2GLA | |
| Water SCHEMBL11254358 | 0.79 | L3MBTL1 (0.45) | PTGDR2TDP1POLBSMN1; SMN2GLA | |
| SCHEMBL71120 | 0.77 | GSTP1 (0.44) | MAPTTDP1POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL14818596 | 0.76 | CDK1 (0.40) | MAPTL3MBTL1 | |
| SCHEMBL71549 | 0.76 | CDK1 (0.41) | MAPT | |
| SCHEMBL31541640 | 0.72 | CDK1 (0.34) | — | |
| SCHEMBL11250024 | 0.71 | ALDH1A1 (0.47) | PTGDR2MAPTTDP1POLBSMN1; SMN2 | |
| SCHEMBL106114 | 0.70 | NPC1 (0.43) | MAPTPOLBSMN1; SMN2 | |
| SCHEMBL11260288 | 0.70 | MAPT (0.44) | PTGDR2MAPTTDP1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324892-A | 7-(N-Substituted-2-phenylglycinamido)-3-substituted-3-cephem-4-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-13 | — | — | US | disclosed |
| US-4172198-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-10-23 | — | — | US | disclosed |