Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | CCND1 | P24385 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | RB1 | P06400 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915324 | 0.84 | CDK1 (0.38) | CDK1CCNB1CDK2CDK4CCND1 | |
| SCHEMBL16748648 | 0.84 | CDK1 (0.38) | CDK1CCNB1CDK2CDK4CCND1 | |
| SCHEMBL16748830 | 0.81 | CDK1 (0.37) | CDK1CCNB1CDK2CDK4CCND1 | |
| SCHEMBL71549 | 0.78 | CDK1 (0.41) | CDK1CCNB1CDK2CDK4CCND1 | |
| SCHEMBL15279055 | 0.77 | CDK1 (0.35) | CDK1CCNB1CDK2CDK4CCND1 | |
| SCHEMBL11259490 | 0.76 | PTGDR2 (0.42) | MAPTL3MBTL1 | |
| SCHEMBL106114 | 0.75 | NPC1 (0.43) | DAONPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL71120 | 0.73 | GSTP1 (0.44) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL15959300 | 0.72 | PTGDR2 (0.33) | CDK1CCNB1CDK2CDK4CCND1 | |
| SCHEMBL410523 | 0.71 | MRGPRX4 (0.41) | DAONPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883773-B2 | Cephem compound having pseudo-catechol group | SHIONOGI & CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20130079319-A1 | CEPHEM COMPOUND HAVING PSEUDO-CATECHOL GROUP | SHIONOGI & CO., LTD. (JP) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079319-A1 | CEPHEM COMPOUND HAVING PSEUDO-CATECHOL GROUP | CENPE, CCNE2, CEP170 | CDK1 188/4885CCNB1 143/4885CDK2 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.