Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 5/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 5/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30549154 | 0.86 | LMNA (0.63) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL3234987 | 0.86 | LMNA (0.63) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL4683288 | 0.85 | LMNA (0.59) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL8897656 | 0.84 | CTRB1 (0.51) | LMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL5123114 | 0.81 | HTT (0.58) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL22300847 | 0.81 | HTT (0.56) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL11527408 | 0.79 | HTT (0.54) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL29262775 | 0.78 | LMNA (0.71) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL11528741 | 0.78 | HTT (0.53) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL7372302 | 0.75 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2L3MBTL1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056408-A1 | GUANYLATED AMINOGLYCOSIDES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICALS | SANDOZ AG (CH) | 1982-07-28 | — | — | EP | disclosed |
| WO-1982000464-A1 | GUANYLATED AMINOGLYCOSIDES,A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICALS | LOIBNER H | 1982-02-18 | — | — | WO | disclosed |