SCHEMBL8897656

SCHEMBL8897656

O=C(OCc1ccccc1)ON1C(=O)c2ccccc2C1=O

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.51
ALDH1A1 P00352 5/20 0.47
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
MAPK1 P28482 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CDC25B P30305 1/20 0.46
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
P2RX4 Q99571 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11529382 0.86 NR1H3 (0.50) ALDH1A1KMT2AMEN1TDP1NPC1
SCHEMBL11259520 0.84 LMNA (0.59) MAPTL3MBTL1LMNASMN1; SMN2
SCHEMBL4041285 0.82 ALDH1A1 (0.49) CTRB1ALDH1A1KMT2AMAPK1L3MBTL1
SCHEMBL31729909 0.82 KMT2A (0.48) CTRB1ALDH1A1KMT2AMAPK1L3MBTL1
SCHEMBL11323517 0.81 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1MAPK1L3MBTL1
SCHEMBL142445 0.81 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1MAPK1L3MBTL1
SCHEMBL2177419 0.80 ALDH1A1 (0.50) ALDH1A1KMT2AMAPTMEN1CYP1A2
SCHEMBL12471113 0.80 L3MBTL1 (0.48) ALDH1A1KMT2AMAPTMEN1CYP1A2
SCHEMBL1279658 0.79 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1MAPK1L3MBTL1
SCHEMBL29034435 0.79 CTRB1 (0.44) CTRB1ALDH1A1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4136254-A PROCESS OF SELECTIVELY BLOCKING AMINO FUNCTIONS IN AMINOGLYCOSIDES USING TRANSITION METAL SALTS AND INTERMEDIATES USED THEREBY SCHERING CORPORATION (US) 1979-01-23 US claimed
US-20250355350-A1 NEGATIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, METHOD FOR FORMING CURED COATING, INTERLAYER INSULATING FILM, SURFACE PROTECTING FILM, AND ELECTRONIC COMPONENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-11-20 US disclosed
EP-4650874-A1 NEGATIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, METHOD FOR FORMING CURED COATING, INTERLAYER INSULATING FILM, SURFACE PROTECTING FILM, AND ELECTRONIC COMPONENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-11-19 EP disclosed
CN-116529302-A Rubber composition, sulfide of the rubber composition, and vulcanized molded article of the rubber composition 电化株式会社 2023-08-01 CN disclosed
CN-116457409-A Chloroprene rubber composition, sulfide of the chloroprene rubber composition, and vulcanized molded article of the chloroprene rubber composition 电化株式会社 2023-07-18 CN disclosed
EP-0547031-B1 N-protected-(S)-isoserine compounds SCHERING CORP (US) 1997-04-23 EP disclosed
US-5539121-A 2-formylmercaptobenzothiazole SCHERING CORPORATION (US) 1996-07-23 US disclosed
US-5442047-A Process for preparing isepamicin SCHERING CORPORATION (US) 1995-08-15 US disclosed
EP-0405820-B1 Improved process for preparing isepamicin SCHERING CORP (US) 1994-04-13 EP disclosed
EP-0547031-A1 N-protected-(S)-isoserine compounds SCHERING CORPORATION (US) 1993-06-16 EP disclosed
US-4298727-A BACTERICIDAL ANTIBIOTICS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) 1981-11-03 US disclosed
US-4297485-A Production of a selectively protected N-acylated derivative of an aminoglycosidic antibiotic ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1981-10-27 US disclosed
US-4283528-A 1-N-aminohydroxyacyl derivatives of gentamicin B SCHERING CORPORATION (US) 1981-08-11 US disclosed
US-4231945-A BACTERICIDES SCHERING CORPORATION (US) 1980-11-04 US disclosed
US-4230847-A Aminoglycoside antibiotic compounds SCHERING CORPORATION (US) 1980-10-28 US disclosed
US-4212859-A OXIMINATION OF AMINO PRECURSOR, ACID HYDROLYSIS, REDUCTION OF OXO GROUP SCHERING CORPORATION (US) 1980-07-15 US disclosed
US-4212860-A COUPLING THE PENTOFURANOSYL ONTO THE PROTECTED CYCLITOL SCHERING CORPORATION (US) 1980-07-15 US disclosed
EP-0000473-A1 Process for preparing aminoglycoside derivatives, novel derivatives obtained and pharmaceutical compositions containing such derivatives Technobiotic Ltd. (CH) 1979-02-07 EP disclosed
US-4136254-A PROCESS OF SELECTIVELY BLOCKING AMINO FUNCTIONS IN AMINOGLYCOSIDES USING TRANSITION METAL SALTS AND INTERMEDIATES USED THEREBY SCHERING CORPORATION (US) 1979-01-23 US disclosed
US-4053591-A 5-DEOXY-4,6-DI-O-(AMINOGLYCOSYL)-1,3-DIAMINOCYCLITOLS, METHODS FOR THEIR MANUFACTURE, METHOD FOR THEIR USE AS ANTIBACTERIAL AGENTS AND COMPOSITIONS USEFUL THEREFOR SCHERING CORPORATION (US) 1977-10-11 US disclosed