Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254722 | 0.94 | HMOX1 (0.39) | HMOX1CYP11B1CYP17A1CYP21A2CYP19A1 | |
| SCHEMBL11257665 | 0.91 | HMOX1 (0.39) | HMOX1CYP11B1CYP17A1CYP21A2CYP19A1 | |
| SCHEMBL11259912 | 0.88 | HMOX1 (0.41) | HMOX1CYP11B1CYP17A1CYP21A2CYP19A1 | |
| SCHEMBL11258048 | 0.87 | CYP17A1 (0.35) | HMOX1CYP11B1CYP17A1CYP21A2CYP19A1 | |
| SCHEMBL11258235 | 0.85 | CYP1A2 (0.41) | HMOX1CYP11B1CYP19A1CYP11B2 | |
| SCHEMBL11261520 | 0.84 | HMOX1 (0.40) | HMOX1CYP11B1CYP17A1CYP21A2CYP19A1 | |
| SCHEMBL11255931 | 0.84 | TSHR (0.42) | CYP19A1ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL11260700 | 0.84 | CYP17A1 (0.35) | HMOX1CYP11B1CYP17A1CYP21A2CYP19A1 | |
| SCHEMBL11270183 | 0.83 | HMOX1 (0.53) | HMOX1 | |
| SCHEMBL11273497 | 0.82 | HMOX1 (0.39) | HMOX1CYP19A1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |