Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269138 | 0.87 | TSHR (0.42) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL11263977 | 0.85 | CYP19A1 (0.41) | ALDH1A1PRKCICYP19A1 | |
| SCHEMBL11252643 | 0.85 | TSHR (0.47) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL11259593 | 0.84 | HMOX1 (0.38) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL11264763 | 0.84 | TSHR (0.39) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL11253398 | 0.83 | ALDH1A1 (0.41) | TSHRALDH1A1MAPK1ALOX15HSD17B10 | |
| SCHEMBL11266636 | 0.82 | MAPK1 (0.40) | ALDH1A1MAPK1ALOX15HSD17B10LMNA | |
| SCHEMBL11261952 | 0.82 | FNTA (0.40) | ALDH1A1LMNACYP19A1 | |
| SCHEMBL11254722 | 0.81 | HMOX1 (0.39) | ALDH1A1MAPK1ALOX15HSD17B10CYP19A1 | |
| SCHEMBL11271243 | 0.80 | QPCT (0.44) | TSHRALDH1A1MAPK1PRKCICYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |