Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260937 | 0.89 | CYP19A1 (0.36) | CYP17A1CYP21A2CYP11B1CYP19A1TSHR | |
| SCHEMBL11256549 | 0.87 | CYP1A2 (0.37) | CYP11B1CYP19A1HMOX1 | |
| SCHEMBL11264763 | 0.85 | TSHR (0.39) | CYP19A1TSHR | |
| SCHEMBL11258556 | 0.85 | HMOX1 (0.47) | HMOX1 | |
| SCHEMBL11258048 | 0.84 | CYP17A1 (0.35) | CYP17A1CYP21A2CYP11B1CYP19A1HMOX1 | |
| SCHEMBL11265343 | 0.84 | HMOX1 (0.34) | HMOX1 | |
| SCHEMBL11259593 | 0.84 | HMOX1 (0.38) | CYP17A1CYP21A2CYP11B1CYP19A1HMOX1 | |
| SCHEMBL11257264 | 0.83 | CYP17A1 (0.38) | CYP17A1CYP21A2CYP11B1CYP19A1HMOX1 | |
| SCHEMBL11253421 | 0.83 | ALDH1A1 (0.37) | CYP11B1CYP19A1TSHR | |
| SCHEMBL11255305 | 0.83 | HMOX1 (0.38) | HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |