Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 11/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252774 | 0.91 | PLA2G2A (0.49) | PPARGPPARAPLA2G2APLA2G1BPOLB | |
| SCHEMBL11259904 | 0.90 | CYP1A2 (0.54) | PPARGPPARAPLA2G2APPARDALDH1A1 | |
| SCHEMBL11257489 | 0.83 | PLA2G2A (0.47) | PPARGPPARAPLA2G2APLA2G1BPOLB | |
| SCHEMBL11257449 | 0.82 | PLA2G2A (0.52) | PPARGPPARAPLA2G2APLA2G1BPPARD | |
| SCHEMBL11258391 | 0.82 | PPARA (0.53) | PPARGPPARAPLA2G2APPARDALDH1A1 | |
| SCHEMBL11256650 | 0.80 | PPARA (0.42) | PPARGPPARAPOLBKDM4ELMNA | |
| SCHEMBL11255001 | 0.80 | GRIK2 (0.52) | PPARGPPARAKDM4EALDH1A1LMNA | |
| SCHEMBL11262300 | 0.80 | PPARG (0.49) | PPARGPPARAPLA2G2APPARDPOLB | |
| SCHEMBL11269239 | 0.79 | KMT2A (0.47) | PPARGPPARAPLA2G2APOLBKDM4E | |
| SCHEMBL11254032 | 0.79 | PPARA (0.46) | PPARGPPARAPLA2G2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |