Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261340 | 0.89 | PPARG (0.53) | PPARGPPARAMEN1KMT2APLA2G4A | |
| SCHEMBL11252774 | 0.89 | PLA2G2A (0.49) | PPARGPPARAMEN1KMT2ACYP1A2 | |
| SCHEMBL11290711 | 0.83 | PPARA (0.47) | PPARGPPARAKMT2ACYP1A2CYP3A4 | |
| SCHEMBL11257489 | 0.81 | PLA2G2A (0.47) | PPARGPPARAMEN1KMT2ACYP1A2 | |
| SCHEMBL11260099 | 0.80 | PPARG (0.47) | PPARGPPARAMEN1KMT2ACYP1A2 | |
| SCHEMBL11258391 | 0.80 | PPARA (0.53) | PPARGPPARAMEN1KMT2ACYP1A2 | |
| SCHEMBL11257449 | 0.80 | PLA2G2A (0.52) | PPARGPPARAMEN1KMT2APLA2G2A | |
| SCHEMBL11264502 | 0.78 | PPARA (0.44) | PPARGPPARAKMT2ACYP1A2CYP3A4 | |
| SCHEMBL11263047 | 0.78 | PPARA (0.46) | PPARGPPARAKMT2ACYP1A2CYP3A4 | |
| SCHEMBL11267723 | 0.77 | PPARA (0.45) | PPARGPPARAKMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343811-A | ATHEROSCLEROSIS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-10 | — | — | US | disclosed |