Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719054 | 0.97 | DPP4 (0.50) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL9798045 | 0.79 | HTR1A (0.37) | DPP4F2LMNA | |
| Hydrochloric Acid SCHEMBL27829280 | 0.78 | DPP4 (0.41) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL27702650 | 0.75 | DPP4 (0.42) | DPP4F2ADRA2AADRA2CLMNA | |
| Hydrochloric Acid SCHEMBL27575683 | 0.74 | MEN1 (0.40) | DPP4F2LMNATAAR1 | |
| Hydrochloric Acid SCHEMBL9420654 | 0.74 | CYP1A2 (0.50) | DPP4F2LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1805114 | 0.72 | TAAR1 (0.41) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL1618600 | 0.70 | CYP1A2 (0.52) | DPP4F2ADRA2AADRA2CLMNA | |
| Ammonia Solution, Strong SCHEMBL27810169 | 0.70 | TAAR1 (0.39) | DPP4F2ADRA2AADRA2CLMNA | |
| Hydrochloric Acid SCHEMBL27724453 | 0.70 | LMNA (0.44) | ADRA2AADRA2CLMNAHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062825-A2 | Water-soluble triazine compounds, their preparation and their use | BAYER AG (DE) | 1982-10-20 | — | — | EP | disclosed |