Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19717288 | 0.88 | LMNA (0.48) | KEAP1NFE2L2RECQLLMNARAB9A | |
| SCHEMBL4025131 | 0.88 | LMNA (0.48) | KEAP1NFE2L2RECQLLMNARAB9A | |
| SCHEMBL28472300 | 0.88 | KMT2A (0.47) | KEAP1NFE2L2RECQLLMNARAB9A | |
| SCHEMBL4025136 | 0.88 | LMNA (0.48) | KEAP1NFE2L2RECQLLMNARAB9A | |
| SCHEMBL8558125 | 0.88 | KMT2A (0.47) | KEAP1NFE2L2RECQLLMNARAB9A | |
| SCHEMBL28264871 | 0.87 | RAB9A (0.40) | KEAP1NFE2L2RECQLLMNARAB9A | |
| SCHEMBL60545 | 0.87 | CYP3A4 (0.51) | RECQLLMNARAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL11988004 | 0.85 | RAB9A (0.45) | KEAP1NFE2L2RECQLLMNARAB9A | |
| SCHEMBL1028817 | 0.85 | RAB9A (0.45) | KEAP1NFE2L2RECQLLMNARAB9A | |
| SCHEMBL584605 | 0.85 | RAB9A (0.45) | KEAP1NFE2L2RECQLLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317920-A | ANTIRHEUMATIC AGENTS, ANTIINFLAMMATORY AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1982-03-02 | — | — | US | claimed |