Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270506 | 0.92 | TBXAS1 (0.51) | POLBCTDSP1TDP1TSHRKMT2A | |
| SCHEMBL11257445 | 0.83 | TBXAS1 (0.58) | EGLN3KMT2ATBXAS1CYP11B1CYP11B2 | |
| SCHEMBL11260214 | 0.82 | KMT2A (0.54) | POLBCTDSP1TDP1EGLN3KMT2A | |
| SCHEMBL11245721 | 0.79 | POLB (0.48) | POLBCTDSP1TDP1EGLN3TSHR | |
| SCHEMBL11269463 | 0.78 | POLB (0.47) | POLBCTDSP1TDP1EGLN3TSHR | |
| SCHEMBL11261485 | 0.76 | TBXAS1 (0.60) | KMT2ATBXAS1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL10785065 | 0.76 | MAPT (0.58) | EGLN3KMT2ATBXAS1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9850522 | 0.75 | CYP11B1 (0.43) | POLBCTDSP1TDP1KMT2ATBXAS1 | |
| SCHEMBL11262682 | 0.75 | TBXAS1 (0.67) | TBXAS1KDM4EALDH1A1QPCT | |
| SCHEMBL28739431 | 0.75 | TSHR (0.52) | POLBCTDSP1TDP1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |