Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245721 | 0.89 | POLB (0.48) | POLBCTDSP1TDP1TBXAS1EGLN3 | |
| SCHEMBL11247258 | 0.89 | TBXAS1 (0.44) | POLBCTDSP1TDP1TBXAS1ALDH1A1 | |
| SCHEMBL11256237 | 0.82 | TBXAS1 (0.43) | POLBCTDSP1TDP1TBXAS1TSHR | |
| SCHEMBL11253750 | 0.82 | CYP19A1 (0.55) | TBXAS1EGLN3CYP11B1CYP11B2 | |
| SCHEMBL11261839 | 0.81 | KDM4E (0.50) | POLBCTDSP1TDP1TBXAS1TSHR | |
| SCHEMBL27927872 | 0.79 | NPSR1 (0.48) | TDP1TSHRALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL11240992 | 0.78 | HMOX2 (0.46) | POLBCTDSP1TDP1TBXAS1ALDH1A1 | |
| SCHEMBL11260433 | 0.78 | POLB (0.50) | POLBCTDSP1TDP1TBXAS1EGLN3 | |
| SCHEMBL11255215 | 0.78 | LMNA (0.50) | TDP1TBXAS1EGLN3KMT2ALMNA | |
| SCHEMBL11241105 | 0.76 | CYP11B1 (0.57) | POLBCTDSP1TDP1TBXAS1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |