Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 4/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262003 | 0.86 | GRM4 (0.41) | GPR35CTSSCTSKPPARGPPARA | |
| SCHEMBL23413926 | 0.82 | GRM8 (0.46) | GRM8GRM4NPC1MAPTRAB9A | |
| SCHEMBL23413613 | 0.82 | CTSS (0.39) | CTSSCTSKPPARGPPARAALOX5 | |
| SCHEMBL3379479 | 0.79 | PPARG (0.54) | CTSSCTSKPPARGPPARAALOX5 | |
| SCHEMBL3379484 | 0.79 | PPARG (0.54) | CTSSCTSKPPARGPPARAALOX5 | |
| SCHEMBL9255604 | 0.78 | ALOX5 (0.55) | CTSSCTSKPPARGPPARAALOX5 | |
| SCHEMBL2238030 | 0.78 | ALOX5 (0.55) | CTSSCTSKPPARGPPARAALOX5 | |
| SCHEMBL2238035 | 0.78 | ALOX5 (0.55) | CTSSCTSKPPARGPPARAALOX5 | |
| SCHEMBL27159466 | 0.76 | CTSS (0.46) | CTSSCTSKPPARGPPARA | |
| SCHEMBL27159468 | 0.76 | CTSS (0.46) | CTSSCTSKPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046734-A2 | Aminohydroxyphenyl derivatives of cephalosporins, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1982-03-03 | — | — | EP | disclosed |