Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.41 |
| ▸ | GRM8 | O00222 | 3/20 | 0.41 |
| ▸ | GRM6 | O15303 | 3/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260747 | 0.86 | GPR35 (0.43) | GRM4GRM8CTSSCTSKMAPT | |
| SCHEMBL23413926 | 0.86 | GRM8 (0.46) | GRM4GRM8GRM6ALDH1A1MAPT | |
| SCHEMBL23413613 | 0.86 | CTSS (0.39) | CTSSCTSKMAPTPPARGPPARA | |
| SCHEMBL10725965 | 0.83 | YARS1 (0.47) | CTSSCTSKGAAMAPTMAPK1 | |
| SCHEMBL3379479 | 0.81 | PPARG (0.54) | ALDH1A1CTSSCTSKGAAMAPT | |
| SCHEMBL11353719 | 0.81 | CTSS (0.44) | CTSSCTSKMAPTPPARGPPARA | |
| SCHEMBL3379484 | 0.81 | PPARG (0.54) | ALDH1A1CTSSCTSKGAAMAPT | |
| SCHEMBL15743379 | 0.80 | FOLH1 (0.54) | CTSSCTSKFOLH1 | |
| SCHEMBL23447574 | 0.80 | CTSS (0.43) | ALDH1A1CTSSCTSKLMNATSHR | |
| SCHEMBL10815323 | 0.80 | S1PR3 (0.45) | CTSSCTSKPPARGPPARAFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046734-A2 | Aminohydroxyphenyl derivatives of cephalosporins, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1982-03-03 | — | — | EP | disclosed |