Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4502145 | 0.80 | HTR2C (0.41) | HDAC6HTR2CKMT2ARAD52MEN1 | |
| SCHEMBL4501912 | 0.79 | KMT2A (0.43) | HTR2CKMT2AMEN1LMNANPSR1 | |
| SCHEMBL11256191 | 0.69 | HDAC6 (0.38) | HDAC6HTR2CKMT2ARAD52MEN1 | |
| SCHEMBL4498347 | 0.68 | WNT3A (0.40) | HTR2CKMT2ARAD52MEN1LMNA | |
| SCHEMBL4503387 | 0.67 | ALDH1A1 (0.47) | HDAC6HTR2CKMT2ARAD52MEN1 | |
| SCHEMBL11256677 | 0.67 | HTR2C (0.42) | HDAC6HTR2CKMT2ARAD52MEN1 | |
| SCHEMBL4512266 | 0.66 | NPC1 (0.45) | HDAC6HTR2CKMT2ARAD52MEN1 | |
| SCHEMBL11255763 | 0.66 | HTR2C (0.41) | HDAC6HTR2CKMT2ARAD52MEN1 | |
| SCHEMBL11732339 | 0.66 | ABL1 (0.56) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL4488488 | 0.65 | HDAC6 (0.50) | HDAC6NPC1RAB9ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |