Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498347 | 0.86 | WNT3A (0.40) | KMT2AMEN1NPSR1LMNAHTR2C | |
| SCHEMBL4502145 | 0.84 | HTR2C (0.41) | KMT2AMEN1NPSR1LMNAHTR2C | |
| SCHEMBL11255745 | 0.84 | HTR2C (0.41) | KMT2AMEN1NPSR1LMNAHTR2C | |
| SCHEMBL4501282 | 0.82 | KMT2A (0.39) | KMT2AMEN1NPSR1LMNA | |
| SCHEMBL11260856 | 0.79 | HDAC6 (0.43) | KMT2AMEN1NPSR1LMNAHTR2C | |
| SCHEMBL11256191 | 0.72 | HDAC6 (0.38) | KMT2AMEN1NPSR1LMNAHTR2C | |
| SCHEMBL11256671 | 0.71 | RAB9A (0.49) | KMT2A | |
| SCHEMBL4503387 | 0.71 | ALDH1A1 (0.47) | KMT2AMEN1LMNAHTR2C | |
| SCHEMBL11256677 | 0.71 | HTR2C (0.42) | KMT2AMEN1NPSR1LMNAHTR2C | |
| SCHEMBL4512266 | 0.70 | NPC1 (0.45) | KMT2AMEN1NPSR1LMNAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258857-A1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-15 | — | — | US | claimed |
| US-8203001-B2 | Chemical compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20090258857-A1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-15 | — | — | US | disclosed |
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258857-A1 | CHEMICAL COMPOUNDS | CCNA1, CCNT1, MKI67 | KMT2A 3467/4885MEN1 18/4885NPSR1 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.