Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255135 | 0.94 | NOTUM (0.44) | NOTUMALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL11256288 | 0.92 | NOTUM (0.40) | NOTUMALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL11254979 | 0.84 | LMNA (0.47) | NOTUMALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL11251598 | 0.83 | CES1 (0.31) | — | |
| SCHEMBL11251007 | 0.80 | SOS1 (0.40) | NOTUMALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL11246023 | 0.79 | PDK2 (0.39) | ALDH1A1KDM4ELMNAL3MBTL1HTT | |
| SCHEMBL11252856 | 0.79 | MMP2 (0.55) | NOTUMALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL11240936 | 0.79 | SOS1 (0.40) | NOTUMALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL11260601 | 0.78 | SOS1 (0.41) | NOTUMALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL11251656 | 0.78 | NOTUM (0.54) | NOTUMALDH1A1KDM4ELMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |