Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260965 | 0.92 | NOTUM (0.45) | NOTUMPDK2KDM4EALDH1A1LMNA | |
| SCHEMBL11255135 | 0.88 | NOTUM (0.44) | NOTUMPDK2KDM4EALDH1A1LMNA | |
| SCHEMBL11254942 | 0.85 | PTGES (0.33) | PTGES | |
| SCHEMBL11242243 | 0.81 | ALDH1A1 (0.46) | NOTUMPDK2KDM4EALDH1A1LMNA | |
| SCHEMBL11254979 | 0.79 | LMNA (0.47) | NOTUMPDK2KDM4EALDH1A1LMNA | |
| SCHEMBL11251809 | 0.79 | PTGES (0.34) | HTTPTGES | |
| SCHEMBL11252326 | 0.78 | PTGES (0.34) | PTGES | |
| SCHEMBL11261743 | 0.78 | PTGES (0.36) | PTGES | |
| SCHEMBL11257668 | 0.77 | PTGES (0.34) | NOTUMTRPV1PTGES | |
| SCHEMBL11244118 | 0.76 | CBFB (0.34) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |