Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215621 | 0.86 | ACE (0.50) | ACEKMT2AALDH1A1 | |
| SCHEMBL11269009 | 0.79 | ACE (0.49) | ACE | |
| SCHEMBL11272121 | 0.78 | ACE (0.43) | ACE | |
| SCHEMBL11413122 | 0.77 | ACE (0.56) | ACE | |
| SCHEMBL7376055 | 0.77 | ACE (0.56) | ACE | |
| SCHEMBL11547230 | 0.76 | ACE (0.51) | ACEALDH1A1 | |
| SCHEMBL11474687 | 0.75 | ACE (0.44) | ACEKMT2AALDH1A1 | |
| SCHEMBL11382290 | 0.73 | ACE (0.67) | ACEALDH1A1 | |
| SCHEMBL11213089 | 0.73 | ACE (0.43) | ACEKMT2AALDH1A1 | |
| SCHEMBL5224593 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330548-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-05-18 | — | — | US | disclosed |
| US-4296113-A | FOR TREATING HYPERTENSION BY INHIBITING ANGIOTENSIN CONVERTING ENZYME | E. R. SQUIBB & SONS, INC. (US) | 1981-10-20 | — | — | US | disclosed |