Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.67 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261524 | 1.00 | MEN1 (0.67) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL11264496 | 0.85 | NPC1 (0.65) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL11264500 | 0.85 | NPC1 (0.65) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL2492862 | 0.80 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL2492861 | 0.80 | MEN1 (1.00) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL11267029 | 0.78 | RAB9A (0.68) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL11267026 | 0.78 | RAB9A (0.68) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL11279469 | 0.78 | RAB9A (0.72) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL11279464 | 0.78 | RAB9A (0.72) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL11829141 | 0.78 | MAPT (0.54) | MEN1KMT2ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329457-A | Process for the preparation of 6-(substituted amino)-3-pyridazinylhydrazines and their salts | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1982-05-11 | — | — | US | disclosed |