Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 11/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267026 | 1.00 | RAB9A (0.68) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL11261524 | 0.78 | MEN1 (0.67) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL11261515 | 0.78 | MEN1 (0.67) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL11279464 | 0.78 | RAB9A (0.72) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL11279469 | 0.78 | RAB9A (0.72) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL11262157 | 0.78 | RAB9A (0.72) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL11262154 | 0.78 | RAB9A (0.72) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL11264500 | 0.69 | NPC1 (0.65) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL11264496 | 0.69 | NPC1 (0.65) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL10740835 | 0.68 | NPC1 (0.51) | RAB9ANPC1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329457-A | Process for the preparation of 6-(substituted amino)-3-pyridazinylhydrazines and their salts | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1982-05-11 | — | — | US | disclosed |