Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266390 | 0.91 | HMOX1 (0.42) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11262771 | 0.91 | CYP1A2 (0.39) | CYP19A1CYP11B1CYP11B2QPCTPOLB | |
| SCHEMBL11261780 | 0.90 | CYP19A1 (0.43) | CYP19A1CYP11B1CYP11B2QPCTPOLB | |
| SCHEMBL11267828 | 0.89 | MEN1 (0.42) | CYP19A1CYP11B1QPCTTDP1ALDH1A1 | |
| SCHEMBL11261555 | 0.89 | KMT2A (0.40) | CYP19A1QPCTPOLBTDP1LMNA | |
| SCHEMBL11269327 | 0.88 | HMOX1 (0.41) | QPCT | |
| SCHEMBL11270017 | 0.87 | QPCT (0.42) | CYP19A1QPCTALDH1A1LMNAPRKCI | |
| SCHEMBL11261648 | 0.86 | POLB (0.40) | CYP11B1CYP11B2QPCTPOLBCTDSP1 | |
| SCHEMBL11261707 | 0.85 | QPCT (0.39) | CYP19A1CYP11B1CYP11B2QPCTALDH1A1 | |
| SCHEMBL11270175 | 0.85 | CYP11B1 (0.51) | CYP19A1CYP11B1CYP11B2QPCTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |