Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11270200 | 0.88 | TP53 (0.42) | TP53POLBALDH1A1TSHRGLA | |
| SCHEMBL11272720 | 0.83 | POLB (0.45) | TP53POLBALDH1A1TSHRGLA | |
| SCHEMBL11249879 | 0.79 | ALDH1A1 (0.37) | TP53POLBALDH1A1TSHRGLA | |
| SCHEMBL11259796 | 0.77 | TP53 (0.46) | TP53POLBALDH1A1TSHRGLA | |
| SCHEMBL11264516 | 0.74 | POLB (0.49) | TP53POLBALDH1A1TSHRGLA | |
| SCHEMBL11261813 | 0.74 | TP53 (0.47) | TP53POLBALDH1A1TSHRGLA | |
| SCHEMBL11267616 | 0.72 | TP53 (0.45) | TP53POLBALDH1A1TSHRGLA | |
| SCHEMBL11274274 | 0.70 | NPC1 (0.43) | TP53ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL11272871 | 0.70 | NPC1 (0.43) | TP53ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL11270036 | 0.70 | NPC1 (0.43) | TP53ALDH1A1TSHRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313892-A | VULCANIZATION INHIBITORS | MONSANTO COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4248805-A | Vulcanizable rubber compositions containing N-(sulfenyl) phthalamides as scorch inhibitors | MONSANTO COMPANY (US) | 1981-02-03 | — | — | US | disclosed |