SCHEMBL11262011

SCHEMBL11262011

Cc1ccc(OP(O)Oc2ccc(C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
CA2 P00918 1/20 0.41
POLB P06746 1/20 0.41
TYR P14679 1/20 0.41
USP2 O75604 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ACHE P22303 1/20 0.36
LMNA P02545 2/20 0.36
TP53 P04637 2/20 0.35
CYP3A4 P08684 2/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
MAPT P10636 2/20 0.34
HSPA5 P11021 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7638739 0.92 SMN1; SMN2 (0.39) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL11267743 0.92 TSHR (0.38) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL30355024 0.91 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL7948556 0.90 USP2 (0.36) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL15377372 0.90 USP2 (0.39) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL10442447 0.90 USP2 (0.36) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL2775176 0.89 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL7948553 0.86 SMN1; SMN2 (0.38) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL10442446 0.86 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2CA2POLBTYR
SCHEMBL10455512 0.85 MRGPRX4 (0.43) ALDH1A1SMN1; SMN2CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4309335-A THERMAL AGING RESISTANCE; ORTHO-SUBSTITUTED PHENYL ACID PHOSPHITE ADEKA ARGUS CHEMICAL CO., LTD. 1982-01-05 US claimed
CN-112423910-B Articles prepared using curable compositions based on polymerizable ionic species 阿科玛法国公司 2022-09-13 CN disclosed
CN-113045736-A Poly (glycolic acid) for containers and films with reduced gas permeability 美国达克有限责任公司 2021-06-29 CN disclosed
CN-104704050-A Polylactic acid resin composition, and method for producing molded article and polylactic acid resin composition TORAY INDUSTRIES 2015-06-10 CN disclosed
US-4348308-A IMPROVING COLOR STABILITY OF VINYL CHLORIDE POLYMERS ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-09-07 US disclosed
US-4309335-A THERMAL AGING RESISTANCE; ORTHO-SUBSTITUTED PHENYL ACID PHOSPHITE ADEKA ARGUS CHEMICAL CO., LTD. 1982-01-05 US disclosed
US-4282141-A DISCOLORATION INHIBITION FOR VINYL CHLORIDE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1981-08-04 US disclosed