SCHEMBL7948556

SCHEMBL7948556

Cc1ccc(OP(O)OF)c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
ALDH1A1 P00352 3/20 0.36
CA2 P00918 1/20 0.36
POLB P06746 1/20 0.36
TYR P14679 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 2/20 0.33
SYK P43405 1/20 0.33
ACHE P22303 1/20 0.32
TP53 P04637 2/20 0.32
MAPT P10636 2/20 0.32
SCN9A Q15858 1/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11262011 0.90 ALDH1A1 (0.41) USP2SMN1; SMN2ALDH1A1CA2POLB
SCHEMBL30355024 0.85 ALDH1A1 (0.37) USP2SMN1; SMN2ALDH1A1CA2POLB
SCHEMBL1705527 0.84 APEX1 (0.36) ALDH1A1CA2TYRMEN1KMT2A
SCHEMBL15377372 0.84 USP2 (0.39) USP2SMN1; SMN2ALDH1A1CA2POLB
SCHEMBL10442447 0.84 USP2 (0.36) USP2SMN1; SMN2ALDH1A1CA2POLB
SCHEMBL7948553 0.83 SMN1; SMN2 (0.38) USP2SMN1; SMN2ALDH1A1CA2POLB
SCHEMBL2775176 0.83 ALDH1A1 (0.41) USP2SMN1; SMN2ALDH1A1CA2POLB
SCHEMBL11267743 0.83 TSHR (0.38) USP2SMN1; SMN2ALDH1A1CA2POLB
SCHEMBL7638739 0.83 SMN1; SMN2 (0.39) USP2SMN1; SMN2ALDH1A1CA2POLB
SCHEMBL7949607 0.80 HSPA5 (0.36) SMN1; SMN2ALDH1A1KMT2ALMNAPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36128-E STABILIZER FOR ORGANIC COMPOUNDS ALBEMARLE CORPORATION (US) 1999-03-02 US claimed
EP-0280938-B1 Antioxidant aromatic fluorophosphites ETHYL CORP (US) 1994-06-15 EP claimed
US-4912155-A Containing substituted aryl group ETHYL CORPORATION (US) 1990-03-27 US claimed
EP-0280938-A1 Antioxidant aromatic fluorophosphites ALBEMARLE CORPORATION (US) 1988-09-07 EP claimed
US-6231804-B1 USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER CHISSO CORPORATION (JP) 2001-05-15 US disclosed
EP-0972800-A1 MODIFIED OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PREPARING THE SAME, AND MODIFIED OLEFIN (CO)POLYMER COMPOSITION MOLDING CHISSO CORPORATION (JP) 2000-01-19 EP disclosed