Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246386 | 0.84 | ALDH1A1 (0.64) | ALDH1A1NPSR1LMNAHSD17B10TSHR | |
| SCHEMBL11240095 | 0.84 | KDM4E (0.60) | ALDH1A1NPSR1LMNAHSD17B10TSHR | |
| SCHEMBL11250952 | 0.82 | MEN1 (0.51) | ALDH1A1NPSR1LMNAHSD17B10TSHR | |
| SCHEMBL11264852 | 0.81 | KDM4E (0.70) | ALDH1A1NPSR1LMNAHSD17B10TSHR | |
| SCHEMBL11247644 | 0.78 | CA1 (0.53) | ALDH1A1NPSR1LMNAHSD17B10TSHR | |
| SCHEMBL11250798 | 0.78 | ALDH1A1 (0.62) | ALDH1A1NPSR1LMNAHSD17B10TSHR | |
| SCHEMBL11255300 | 0.78 | ALDH1A1 (0.55) | ALDH1A1NPSR1LMNAHSD17B10TSHR | |
| SCHEMBL11246134 | 0.77 | KDM4E (0.56) | ALDH1A1NPSR1LMNAHSD17B10TSHR | |
| SCHEMBL11764115 | 0.77 | RAB9A (0.46) | ALDH1A1NPSR1LMNAMEN1KMT2A | |
| SCHEMBL11728680 | 0.77 | KDM4E (0.50) | ALDH1A1NPSR1HSD17B10TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |