Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259222 | 0.86 | NPC1 (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11262352 | 0.85 | MAPT (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11262236 | 0.85 | MAPT (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11271207 | 0.85 | MAPT (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11266789 | 0.81 | MAPT (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11264221 | 0.81 | NPC1 (0.45) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11269414 | 0.81 | KMT2A (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11256671 | 0.80 | RAB9A (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL4509401 | 0.79 | RAB9A (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL4493348 | 0.75 | CASP2 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |