Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198284 | 0.82 | POLB (0.44) | POLBHPGDKMT2AMEN1CYP19A1 | |
| SCHEMBL11198126 | 0.81 | POLB (0.44) | POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL11185825 | 0.80 | POLB (0.45) | POLBHPGDKMT2AMEN1CYP19A1 | |
| SCHEMBL11179656 | 0.80 | POLB (0.40) | POLBHPGDKMT2AMEN1CYP19A1 | |
| SCHEMBL11187781 | 0.79 | MAPK1 (0.45) | POLBHPGDKMT2AMEN1CYP19A1 | |
| SCHEMBL11188460 | 0.79 | CYP19A1 (0.46) | POLBHPGDKMT2AMEN1CYP19A1 | |
| SCHEMBL5544140 | 0.75 | TSHR (0.58) | POLBHPGDKMT2AMEN1CYP19A1 | |
| SCHEMBL7783933 | 0.75 | TSHR (0.58) | POLBHPGDKMT2AMEN1CYP19A1 | |
| SCHEMBL11272488 | 0.74 | ADRA2C (0.52) | KMT2AMEN1CYP19A1 | |
| SCHEMBL10823260 | 0.74 | KCNH2 (0.51) | POLBHPGDKMT2AMEN1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349556-A | Pesticidally active 1-acyloxy-1-phenyl-2-azolyl-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-14 | — | — | US | disclosed |