Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.44 |
| ▸ | CHRNG | P07510 | 2/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CHRND | Q07001 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30327087 | 0.83 | LMNA (0.47) | PARP1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL24028298 | 0.79 | PARP1 (0.52) | PARP1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL27406291 | 0.77 | KMO (0.55) | MEN1KMT2AGAAMAPTERCC5 | |
| SCHEMBL9628068 | 0.77 | CES2 (0.48) | KMT2AALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL8151048 | 0.77 | LMNA (0.48) | PARP1MEN1KMT2AALDH1A1GAA | |
| SCHEMBL21448791 | 0.76 | TSHR (0.52) | MEN1KMT2AMAPTHPGDSLC6A2 | |
| SCHEMBL13753617 | 0.75 | TP53 (0.56) | MEN1KMT2ATP53ALDH1A1L3MBTL1 | |
| SCHEMBL35211536 | 0.75 | PARP1 (0.47) | PARP1MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL26145005 | 0.74 | CA12 (0.44) | MEN1KMT2ATP53ALDH1A1GAA | |
| SCHEMBL17187940 | 0.72 | PARP1 (0.63) | PARP1MEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |