Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141378 | 0.81 | TSHR (0.57) | ALDH1A1MEN1KMT2AKDM4EFLT1 | |
| SCHEMBL12442147 | 0.81 | KMT2A (0.50) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9267287 | 0.79 | ABL1 (0.53) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL23175682 | 0.79 | KMT2A (0.55) | ALDH1A1MEN1KMT2AMGLL | |
| SCHEMBL8629071 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL13261321 | 0.77 | CHRM1 (0.50) | ALDH1A1MEN1KMT2AMGLL | |
| SCHEMBL24076267 | 0.77 | ABL1 (0.55) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL250256 | 0.77 | FLT1 (0.53) | ALDH1A1MEN1KMT2AFLT1FLT4 | |
| SCHEMBL20855926 | 0.76 | CA1 (0.58) | ALDH1A1LMNAMEN1KMT2APKM | |
| SCHEMBL12859803 | 0.76 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |