SCHEMBL250256

SCHEMBL250256

Cc1cc(Cl)ccc1C(=O)c1ccc(Cl)cc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 1/20 0.53
FLT4 P35916 1/20 0.53
KDR P35968 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.48
TSHR P16473 2/20 0.48
CASP1 P29466 1/20 0.48
CYP11B2 P19099 1/20 0.47
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.47
MAPT P10636 1/20 0.47
SRD5A2 P31213 1/20 0.47
MYC P01106 1/20 0.46
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
HTR2B P41595 1/20 0.44
ABL1 P00519 1/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 1/20 0.44
HIF1A Q16665 1/20 0.44
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4437961 0.90 MAPK13 (0.55) FLT1FLT4KDRCYP11B2RAB9A
SCHEMBL10627982 0.90 SRD5A2 (0.56) FLT1FLT4KDRSMN1; SMN2RAB9A
SCHEMBL9422061 0.86 CES2 (0.55) SMN1; SMN2RAB9ANPC1MAPTSRD5A2
SCHEMBL28758089 0.85 NR4A1 (0.56) RAB9AMAPTSRD5A2ALDH1A1TP53
SCHEMBL10775755 0.85 MAPK1 (0.60) FLT1FLT4KDRSMN1; SMN2RAB9A
SCHEMBL30628195 0.84 FLT1 (0.51) FLT1FLT4KDRSMN1; SMN2TSHR
SCHEMBL4574528 0.84 FLT1 (0.51) FLT1FLT4KDRSMN1; SMN2TSHR
SCHEMBL109654 0.84 SMN1; SMN2 (0.63) FLT1FLT4KDRSMN1; SMN2TSHR
SCHEMBL107882 0.84 FLT1 (0.51) FLT1FLT4KDRSMN1; SMN2TSHR
SCHEMBL5174662 0.84 RAB9A (0.48) FLT1FLT4KDRSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9005843-B2 Polymer electrolyte composition UBE INDUSTRIES, LTD. (JP) 2015-04-14 US disclosed
US-8710176-B2 Method for producing a sulfonated polyarylether block copolymer UBE INDUSTRIES, LTD. (JP) 2014-04-29 US disclosed
EP-2362472-B1 Production method for polymer electrolyte UBE INDUSTRIES (JP) 2012-10-24 EP disclosed
EP-2362473-B1 Producion method for polymer electrolyte UBE INDUSTRIES (JP) 2012-10-24 EP disclosed
US-20120264835-A1 METHOD FOR PRODUCING A SULFONATED POLYARYLETHER BLOCK COPOLYMER UBE INDUESTIRES, LTD. (JP) 2012-10-18 US disclosed
EP-2355218-B1 Novel polymer electrolyte, polymer electrolyte composition, electrolyte membrane, and production method and use thereof UBE INDUSTRIES (JP) 2012-10-03 EP disclosed
US-20120171598-A1 POLYMER ELECTROLYTE COMPOSITION UBE INDUSTRIES, LTD. (JP) 2012-07-05 US disclosed
US-20120164557-A1 METHOD FOR PRODUCING A POLYMER ELECTROLYTE MEMBRANE UBE INDUSTRIES, LTD. (JP) 2012-06-28 US disclosed
EP-1855339-B1 NOVEL POLYMER ELECTROLYTE, POLYMER ELECTROLYTE COMPOSITION, ELECTROLYTE MEMBRANE, AND PRODUCTION METHOD AND USE THEREOF UBE INDUSTRIES (JP) 2012-01-04 EP disclosed
EP-2362473-A1 Novel polymer electrolyte, polymer electrolyte composition, electrolyte membrane, and production method and use thereof Ube Industries, Ltd. (JP) 2011-08-31 EP disclosed
EP-2362472-A1 Novel polymer electrolyte, polymer electrolyte composition, electrolyte membrane, and production method and use thereof Ube Industries, Ltd. (JP) 2011-08-31 EP disclosed
EP-2355218-A1 Novel polymer electrolyte, polymer electrolyte composition, electrolyte membrane, and production method and use thereof Ube Industries, Ltd. (JP) 2011-08-10 EP disclosed
US-20080171252-A1 Novel Polymer Electrolyte, Polymer Electrolyte Composition, Electrolyte Membrane, and Production Method and Use Thereof UBE INDUSTRIES, LTD. (JP) 2008-07-17 US disclosed
EP-1855339-A1 NOVEL POLYMER ELECTROLYTE, POLYMER ELECTROLYTE COMPOSITION, ELECTROLYTE MEMBRANE, AND PRODUCTION METHOD AND USE THEREOF Ube Industries, Ltd. (JP) 2007-11-14 EP disclosed
EP-0162606-B1 AROMATIC POLYTHIOETHERAMIDES AND PROCESS FOR THEIR PRODUCTION MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-01-25 EP disclosed
US-4621134-A Aromatic polythioetheramide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-11-04 US disclosed
EP-0162606-A1 Aromatic polythioetheramides and process for their production MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1985-11-27 EP disclosed
US-4134917-A Method for the denitrosation of organic nitrosamines AMERICAN CYANAMID COMPANY (US) 1979-01-16 US disclosed