Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935499 | 0.82 | MAPT (0.69) | MAPTCA12SOS1NPSR1MAOB | |
| SCHEMBL11049170 | 0.82 | MAPT (0.69) | MAPTCA12SOS1NPSR1MAOB | |
| SCHEMBL9978289 | 0.82 | MAPT (0.69) | MAPTCA12SOS1NPSR1MAOB | |
| SCHEMBL114440 | 0.82 | MAPT (0.58) | MAPTCA12SOS1XDHNPSR1 | |
| SCHEMBL11296000 | 0.80 | MAPT (0.67) | MAPTCA12SOS1NPSR1MAOB | |
| 2-Nitrobenzaldehyde SCHEMBL5654 | 0.80 | ERN1 (0.66) | MAPTCA12SOS1XDHNPSR1 | |
| 2-Nitrobenzaldehyde SCHEMBL29672618 | 0.80 | ERN1 (0.66) | MAPTCA12SOS1XDHNPSR1 | |
| SCHEMBL11299049 | 0.80 | MAPT (0.67) | MAPTCA12SOS1NPSR1MAOB | |
| SCHEMBL4361353 | 0.79 | MAPT (0.61) | MAPTSOS1MAOBMEN1KMT2A | |
| SCHEMBL4307048 | 0.79 | MAPT (0.61) | MAPTSOS1MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10894803-B2 | Multi-functionalized polysaccharide compounds and use thereof for targeting the cation-independent mannose 6-phosphate receptor | NANOMEDSYN (FR) | 2021-01-19 | — | — | US | disclosed |
| US-20180265534-A1 | MULTI-FUNCTIONALIZED POLYSACCHARIDE COMPOUNDS AND USE THEREOF FOR TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-09-20 | — | — | US | disclosed |
| US-4341706-A | Process for the preparation of carbapenem antibiotics | MERCK & CO., INC. (US) | 1982-07-27 | — | — | US | disclosed |
| US-4262009-A | AMINO ACID DERIVATIVE ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4262011-A | AMINO ACID DERIVATIVE ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4208422-A | ANTIBIOTICS, BACTERICIDES | MERCK & CO., INC. (US) | 1980-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180265534-A1 | MULTI-FUNCTIONALIZED POLYSACCHARIDE COMPOUNDS AND USE THEREOF FOR TARGETING THE CATION-INDEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR | M6PR, IGF2R, MPI | MAPT 3933/4885CA12 196/4885SOS1 4433/4885 |
| US-10894803-B2 | Multi-functionalized polysaccharide compounds and use thereof for targeting the cation-independent mannose 6-phosphate receptor | M6PR, IGF2R, MPI | MAPT 3885/4885CA12 229/4885SOS1 4388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.