Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18648462 | 0.80 | HTR2A (0.42) | SLC6A2SLC6A4ADRA1AKCNH2ADRA2A | |
| SCHEMBL15222054 | 0.78 | POLB (0.51) | MTNR1ASRD5A1MEN1KMT2ACHRM2 | |
| SCHEMBL29659945 | 0.78 | POLB (0.51) | MTNR1ASRD5A1MEN1KMT2ACHRM2 | |
| SCHEMBL811848 | 0.78 | POLB (0.51) | MTNR1ASRD5A1MEN1KMT2ACHRM2 | |
| SCHEMBL9230128 | 0.78 | POLB (0.51) | MTNR1ASRD5A1MEN1KMT2ACHRM2 | |
| SCHEMBL23505301 | 0.77 | MTNR1A (0.49) | MTNR1ASRD5A1ALDH1A1MEN1USP2 | |
| SCHEMBL28842199 | 0.77 | MTNR1A (0.46) | MTNR1ASRD5A1ALDH1A1MEN1USP2 | |
| SCHEMBL30018725 | 0.77 | MTNR1A (0.46) | MTNR1ASRD5A1ALDH1A1MEN1USP2 | |
| SCHEMBL28136142 | 0.77 | MTNR1A (0.46) | MTNR1ASRD5A1ALDH1A1MEN1USP2 | |
| SCHEMBL21312439 | 0.77 | HDAC1 (0.48) | MTNR1ASRD5A1CHRM2CHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047671-A1 | Penicillanoyloxymethyl penicillanate 1,1,1'-tetraoxide | PFIZER INC. (US) | 1982-03-17 | — | — | EP | disclosed |