SCHEMBL11262853

SCHEMBL11262853

CCO[SiH](OCC)C(C)Br

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29201696 0.78 HSD17B10 (0.32)
SCHEMBL26982671 0.75 LMNA (0.35) LMNA
SCHEMBL66057 0.75 LMNA (0.35) LMNA
SCHEMBL29201679 0.74
SCHEMBL29201639 0.74
SCHEMBL29201670 0.72
SCHEMBL4081969 0.72
SCHEMBL8851698 0.71 LMNA (0.32) LMNA
SCHEMBL134645 0.71 OPRM1 (0.32) LMNA
SCHEMBL125174 0.71 LMNA (0.32) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4366184-A PLASMA/GASES/, ORGANOSILICON COMPOUND LORD CORPORATION (US) 1982-12-28 US disclosed
US-4143060-A REACTING AN ISOCYANATO- SUBSTITUTED SILAIMIDAZOLIDONE DERIVATIVE WITH A URETHANE CONTAINING POLYMER BAYER AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-3933756-A Process of preparation of synthetic resins by reacting a cross-linked isocyanate polyaddition product with low molecular weight polyisocyanate followed by reaction with an amino alkyl silane BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed