Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | RXRB | P28702 | 3/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273586 | 0.86 | PTGS2 (0.41) | PTGS2ESR2RXRADOT1LMEN1 | |
| SCHEMBL11264953 | 0.77 | CYP1A2 (0.43) | RXRARXRBRXRGMEN1NFKB1 | |
| SCHEMBL11270290 | 0.76 | PTGS2 (0.39) | PTGS2ESR2MAPK1NPC1MEN1 | |
| SCHEMBL11263881 | 0.73 | L3MBTL1 (0.46) | RXRARXRBRXRGMEN1NFKB1 | |
| SCHEMBL10913732 | 0.72 | PTGS2 (0.44) | PTGS2ESR2RXRAMEN1KMT2A | |
| SCHEMBL10981401 | 0.70 | PTGS2 (0.42) | PTGS2ESR2RXRARXRBRXRG | |
| SCHEMBL11435307 | 0.68 | MAPK1 (0.46) | PTGS2MAPK1HDAC3HDAC1HDAC2 | |
| SCHEMBL10915632 | 0.67 | PTGS2 (0.39) | PTGS2RXRAMAPK1GRIA1NPC1 | |
| SCHEMBL13557867 | 0.66 | KDM4E (0.47) | MAPK1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL11453631 | 0.66 | PTGS2 (0.43) | PTGS2MAPK1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358307-A | PREFERENTIAL CONTROLLING OF MONOCOTYLEDONS IN CROPS | ICI AUSTRALIA LIMITED (AU) | 1982-11-09 | — | — | US | disclosed |
| EP-0026622-A2 | Quinoxalinylaminophenoxyalkane carboxylic acid derivatives, their preparation, their use as herbicides and intermediates | ICI AUSTRALIA LIMITED (AU) | 1981-04-08 | — | — | EP | disclosed |