SCHEMBL11263221

SCHEMBL11263221

OC(Cn1ccnc1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.63
HMOX1 P09601 1/20 0.59
CYP51A1 Q16850 1/20 0.55
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11268521 0.88 CYP19A1 (0.62) CYP19A1HMOX1CYP51A1
SCHEMBL6173273 0.87 CYP19A1 (0.71) CYP19A1HMOX1CYP51A1
SCHEMBL6299346 0.87 CYP19A1 (0.71) CYP19A1HMOX1CYP51A1
SCHEMBL11147343 0.86 CYP19A1 (0.57) CYP19A1
SCHEMBL11146856 0.85 CYP19A1 (0.60) CYP19A1
SCHEMBL11150973 0.84 TBXAS1 (0.56) CYP19A1
SCHEMBL11152025 0.84 POLB (0.46) CYP19A1POLB
SCHEMBL11270111 0.84 HMOX1 (0.76) CYP19A1HMOX1CYP51A1
SCHEMBL8836204 0.83 CYP19A1 (0.67) CYP19A1HMOX1CYP51A1
Denzimol SCHEMBL2110767 0.82 CYP19A1 (0.65) CYP19A1HMOX1CYP51A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4349556-A Pesticidally active 1-acyloxy-1-phenyl-2-azolyl-ethanes BAYER AKTIENGESELLSCHAFT (DE) 1982-09-14 US disclosed