Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.76 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.68 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.59 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173273 | 0.91 | CYP19A1 (0.71) | HMOX1CYP19A1CYP51A1 | |
| SCHEMBL6299346 | 0.91 | CYP19A1 (0.71) | HMOX1CYP19A1CYP51A1 | |
| SCHEMBL9996056 | 0.87 | HMOX1 (1.00) | HMOX1CYP19A1CYP51A1 | |
| Denzimol SCHEMBL2110767 | 0.85 | CYP19A1 (0.65) | HMOX1CYP19A1CYP51A1 | |
| SCHEMBL11263221 | 0.84 | CYP19A1 (0.63) | HMOX1CYP19A1CYP51A1 | |
| SCHEMBL10932073 | 0.82 | CYP19A1 (0.73) | HMOX1CYP19A1CYP51A1CYP11B1 | |
| SCHEMBL7562437 | 0.81 | CYP19A1 (0.72) | HMOX1CYP19A1CYP51A1 | |
| SCHEMBL11266884 | 0.81 | CYP19A1 (0.72) | HMOX1CYP19A1CYP51A1CYP11B1CYP11B2 | |
| SCHEMBL6299999 | 0.81 | CYP19A1 (0.72) | HMOX1CYP19A1CYP51A1 | |
| SCHEMBL11983140 | 0.81 | CYP19A1 (0.72) | HMOX1CYP19A1CYP51A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349556-A | Pesticidally active 1-acyloxy-1-phenyl-2-azolyl-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-14 | — | — | US | disclosed |
| US-4275071-A | Imidazole derivatives | RECORDATI S.A. (CH) | 1981-06-23 | — | — | US | disclosed |