Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | HAT1 | O14929 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18878436 | 0.78 | HTR4 (0.44) | PTPN2PTPN1ALDH1A1MAPTKDM4E | |
| SCHEMBL18891540 | 0.73 | LMNA (0.41) | PTPN2PTPN1ALDH1A1MAPTKDM4E | |
| SCHEMBL8234959 | 0.70 | PTPN1 (0.60) | PTPN2PTPN1ALDH1A1MAPTKDM4E | |
| SCHEMBL20674534 | 0.69 | PTPN2 (0.44) | PTPN2PTPN1ALDH1A1MAPTKDM4E | |
| SCHEMBL13377445 | 0.68 | ALDH1A1 (0.41) | PTPN2PTPN1ALDH1A1MAPTKDM4E | |
| SCHEMBL22276461 | 0.68 | HTR4 (0.39) | HTR4 | |
| SCHEMBL17520300 | 0.67 | PTPN2 (0.43) | PTPN2PTPN1ALDH1A1MAPTKDM4E | |
| SCHEMBL19100335 | 0.67 | PTPN1 (0.43) | PTPN2PTPN1ALDH1A1MAPTKDM4E | |
| SCHEMBL22339347 | 0.66 | SSTR4 (0.48) | PTPN2PTPN1ALDH1A1MAPTKDM4E | |
| SCHEMBL18032960 | 0.65 | DRD4 (0.41) | PTPN2PTPN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361567-A | IMIDAZO(1,5-A)PYRIDINES | SCHERING CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |