SCHEMBL11263272

SCHEMBL11263272

CCCCC1CCSC(CCn2ccnc2)(Cc2ccccc2)S1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36
CYP2C19 P33261 1/20 0.36
QPCT Q16769 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TBXAS1 P24557 3/20 0.36
CYP19A1 P11511 3/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
CYP4Z1 Q86W10 1/20 0.36
QPCTL Q9NXS2 1/20 0.36
LTA4H P09960 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11259161 0.95 TBXAS1 (0.38) CYP1A2CYP3A4CYP2D6CYP2C9ALOX15
SCHEMBL11260829 0.92 QPCT (0.39) QPCTSMN1; SMN2TBXAS1CYP19A1
SCHEMBL11256422 0.91 HMOX1 (0.37) CYP1A2CYP3A4CYP2D6CYP2C9ALOX15
SCHEMBL11263880 0.91 CYP2A6 (0.39) QPCTCYP19A1CYP11B1CYP11B2
SCHEMBL11261533 0.90 CYP1A2 (0.37) CYP1A2CYP3A4CYP2D6CYP2C9ALOX15
SCHEMBL11256558 0.90 CYP1A2 (0.37) CYP1A2CYP3A4CYP2D6CYP2C9ALOX15
SCHEMBL11262771 0.90 CYP1A2 (0.39) CYP1A2CYP3A4CYP2D6CYP2C9ALOX15
SCHEMBL11263441 0.89 MEN1 (0.41) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL11261707 0.87 QPCT (0.39) QPCTTBXAS1CYP19A1CYP11B1CYP11B2
SCHEMBL11270666 0.86 CYP2A6 (0.38) QPCTCYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359475-A SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS SYNTEX (U.S.A.) INC. (US) 1982-11-16 US disclosed