Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260969 | 0.83 | KDM4E (0.46) | KDM4EBCHECYP1A2CYP2D6LMNA | |
| SCHEMBL11265796 | 0.76 | LMNA (0.54) | KDM4EBCHECYP2D6LMNASMN1; SMN2 | |
| SCHEMBL11267936 | 0.76 | KDM4E (0.50) | KDM4EBCHESMN1; SMN2ANPEPERAP2 | |
| SCHEMBL654773 | 0.72 | CA1 (0.58) | KDM4ELMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9494959 | 0.70 | CA1 (0.56) | KDM4ELMNAALDH1A1 | |
| SCHEMBL20813364 | 0.70 | CA12 (0.44) | KDM4ELMNANPC1ALDH1A1 | |
| SCHEMBL27794285 | 0.69 | SERPINE1 (0.53) | CYP1A2CYP2D6LMNANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11269336 | 0.69 | KDM4E (0.52) | KDM4EBCHELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL15054040 | 0.69 | ATAD2 (0.44) | KDM4ELMNANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1765176 | 0.69 | DHODH (0.60) | KDM4ECYP1A2CYP2D6NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337272-A | BRONCHODILATOR AGENTS | VALEAS S. R. L. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1982-06-29 | — | — | US | disclosed |
| US-4252824-A | BRONCHODILATOR AGENTS | VALEAS S.R.L., INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1981-02-24 | — | — | US | disclosed |