Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | APEX1 | P27695 | 3/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.35 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.35 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29894018 | 0.81 | APEX1 (0.54) | POLBAPEX1CTDSP1L3MBTL1KDM4E | |
| SCHEMBL8769752 | 0.80 | POLB (0.71) | POLBAPEX1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL28231 | 0.79 | POLB (1.00) | POLBKDM4EALDH1A1HPGDGABRA1 | |
| SCHEMBL27811882 | 0.79 | APEX1 (0.52) | POLBAPEX1CTDSP1L3MBTL1KDM4E | |
| SCHEMBL29420401 | 0.79 | POLB (1.00) | POLBKDM4EALDH1A1HPGDGABRA1 | |
| SCHEMBL3403169 | 0.79 | POLB (1.00) | POLBKDM4EALDH1A1HPGDGABRA1 | |
| SCHEMBL29375900 | 0.79 | POLB (1.00) | POLBKDM4EALDH1A1HPGDGABRA1 | |
| SCHEMBL278481 | 0.79 | KDM4E (0.46) | POLBL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL2053985 | 0.78 | GABRA1 (0.41) | POLBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL17769822 | 0.78 | ALDH1A1 (0.55) | POLBALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31103-E | HEAT RESISTANT DIELECTRIC FLUOROPOLYMERS | RAYCHEM CORPORATION (US) | 1982-12-14 | — | — | US | claimed |
| US-4121001-A | IMIDE OR DIIMIDE | RAYCHEM CORPORATION (US) | 1978-10-17 | — | — | US | claimed |
| US-RE31103-E | HEAT RESISTANT DIELECTRIC FLUOROPOLYMERS | RAYCHEM CORPORATION (US) | 1982-12-14 | — | — | US | disclosed |