Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.35 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22160245 | 0.96 | GABRA1 (0.38) | GABRA1GABRB2PTGDRPTGDR2POLB | |
| SCHEMBL6535892 | 0.93 | GABRA1 (0.39) | GABRA1GABRB2PTGDRPTGDR2POLB | |
| SCHEMBL29225947 | 0.91 | GABRA1 (0.41) | GABRA1GABRB2PTGDRPTGDR2POLB | |
| SCHEMBL9081528 | 0.89 | IDO1 (0.42) | GABRA1GABRB2PTGDRPTGDR2POLB | |
| SCHEMBL5175262 | 0.85 | GAA (0.39) | GABRA1GABRB2PTGDRPTGDR2POLB | |
| SCHEMBL278481 | 0.84 | KDM4E (0.46) | GABRA1GABRB2PTGDRPTGDR2POLB | |
| SCHEMBL28227972 | 0.83 | IDO1 (0.49) | POLBALDH1A1MAPTHSD17B10KDM4E | |
| SCHEMBL2852455 | 0.82 | ALDH1A1 (0.53) | GABRA1GABRB2PTGDRPTGDR2POLB | |
| SCHEMBL5175539 | 0.82 | TSHR (0.37) | GABRA1GABRB2PTGDRPTGDR2POLB | |
| SCHEMBL1908071 | 0.82 | ALDH1A1 (0.52) | GABRA1GABRB2PTGDRPTGDR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8525131-B2 | Phosphorescent organic compounds | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2013-09-03 | — | — | US | disclosed |
| US-20120248337-A1 | PHOSPHORESCENT ORGANIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-10-04 | — | — | US | disclosed |
| WO-2011066415-A2 | PHOSPHORESCENT ORGANIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120248337-A1 | PHOSPHORESCENT ORGANIC COMPOUNDS | PAICS, PPIP5K2, PPA1 | GABRA1 3946/4885GABRB2 4313/4885PTGDR 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.