Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265227 | 0.86 | HSD17B10 (0.46) | POLBTDP1PDE4BALDH1A1CYP1A2 | |
| SCHEMBL11260711 | 0.83 | GPBAR1 (0.46) | SLC6A4ALDH1A1HPGDPTGDR2TSHR | |
| SCHEMBL11259607 | 0.82 | MAPT (0.44) | POLBTDP1KCNH2ALDH1A1MEN1 | |
| SCHEMBL11264258 | 0.81 | POLB (0.45) | POLBPDE4BALDH1A1CYP1A2HPGD | |
| SCHEMBL11263458 | 0.80 | GPBAR1 (0.45) | SLC6A4ALDH1A1HPGDPTGDR2TSHR | |
| SCHEMBL11267799 | 0.80 | GPBAR1 (0.42) | SLC6A4ALDH1A1PTGDR2TSHRSMN1; SMN2 | |
| SCHEMBL11260689 | 0.76 | GPBAR1 (0.47) | SLC6A4ALDH1A1HPGDPTGDR2TSHR | |
| SCHEMBL11257808 | 0.74 | MAPT (0.44) | POLBTDP1KCNH2ALDH1A1MEN1 | |
| SCHEMBL3337091 | 0.74 | GPBAR1 (0.38) | SLC6A4ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL9687675 | 0.72 | POLB (0.56) | POLBPDE4BALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322439-A | ω-[2-(N-Lower alkyl-benzamido)-phenyl]-alkanoic acids, their use, and medicaments containing them | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-03-30 | — | — | US | disclosed |
| WO-1979000586-A1 | W-(2-N-LOWER ALKYL-BENZAMIDO)-PHENYL)-ALKANOIC ACIDS,THEIR USE AND PREPARATION,AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1979-08-23 | — | — | WO | disclosed |