Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151144 | 0.77 | PTGS1 (0.53) | MLYCDMEN1KMT2A | |
| SCHEMBL2118466 | 0.76 | TRPV1 (0.44) | MLYCDMEN1KMT2ATRPV1GPBAR1 | |
| SCHEMBL2120590 | 0.76 | TRPV1 (0.58) | MEN1KMT2ATRPV1GPBAR1STAT3 | |
| SCHEMBL11267587 | 0.73 | TRPV1 (0.48) | MEN1KMT2ATRPV1KIF11CASP3 | |
| SCHEMBL2117873 | 0.68 | PTGS1 (0.47) | MEN1KMT2ATRPV1GPBAR1STAT3 | |
| SCHEMBL4424848 | 0.68 | MLYCD (1.00) | MLYCDMAPK14 | |
| SCHEMBL16739695 | 0.67 | PLAU (0.60) | MKNK1MKNK2KIF11 | |
| SCHEMBL22925912 | 0.67 | NOTUM (0.61) | KIF11CASP3S1PR1S1PR3 | |
| SCHEMBL5775028 | 0.67 | GABRA5 (0.52) | MLYCDMEN1KMT2AKIF11GPBAR1 | |
| SCHEMBL8764860 | 0.66 | MLYCD (0.44) | MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336264-A | 1-Benzoyl-3-(isoxazolyl or benzisoxazolyl)-ureas and insecticidal use thereof | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | disclosed |